The DAND5 antibody from MyBioSource.com is a Mouse Monoclonal antibody to CER2, COCO, and DAND5. This antibody recognizes Human antigen. The DAND5 antibody has been validated for the following applications: Flow Cytometry, Immunohistochemistry, and Western Blot.
Description
Mouse monoclonal DAND5 antibody
DAND5 is a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists containcystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. In mouse, this protein has been shown to bind Nodal and to inhibit the Nodal signaling pathway which patterns left/right body asymmetry